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1

Aldosterone and amiloride alter ENaC abundance in vascular endothelium

Kristina Kusche-Vihrog, Katja Sobczak, Nadine Bangel, Marianne Wilhelmi, Volodymyr Nechyporuk-Zloy, Albrecht Schwab, Hermann Schillers, Hans Oberleithner

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2008

Language:

english

File:

PDF, 260 KB

english, 2008

2

Aldosterone receptor sites on plasma membrane of human vascular endothelium detected by a mechanical nanosensor

L. Wildling, P. Hinterdorfer, K. Kusche-Vihrog, Y. Treffner, H. Oberleithner

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2009

Language:

english

File:

PDF, 257 KB

english, 2009

3

Nitric oxide release follows endothelial nanomechanics and not vice versa

Johannes Fels, Chiara Callies, Kristina Kusche-Vihrog, Hans Oberleithner

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2010

Language:

english

File:

PDF, 520 KB

english, 2010

4

Salt overload damages the glycocalyx sodium barrier of vascular endothelium

Hans Oberleithner, Wladimir Peters, Kristina Kusche-Vihrog, Stefanie Korte, Hermann Schillers, Katrin Kliche, Kilian Oberleithner

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2011

Language:

english

File:

PDF, 618 KB

english, 2011

5

Firewall function of the endothelial glycocalyx in the regulation of sodium homeostasis

Stefanie Korte, Anne Wiesinger, Alexandra S. Straeter, Wladimir Peters, Hans Oberleithner, Kristina Kusche-Vihrog

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2012

Language:

english

File:

PDF, 536 KB

english, 2012

6

Ménage à trois: Aldosterone, sodium and nitric oxide in vascular endothelium

Johannes Fels, Hans Oberleithner, Kristina Kusche-Vihrog

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2010

Language:

english

File:

PDF, 1.05 MB

english, 2010

7

The epithelial sodium channel (ENaC): Mediator of the aldosterone response in the vascular endothelium?

Kristina Kusche-Vihrog, Chiara Callies, Johannes Fels, Hans Oberleithner

Journal:

Year:

2010

Language:

english

File:

PDF, 620 KB

english, 2010

8

An emerging concept of vascular salt sensitivity

Kusche-Vihrog, Kristina, Oberleithner, Hans

Journal:

F1000 Biology Reports

Year:

2012

Language:

english

File:

PDF, 297 KB

english, 2012

9

Upregulated expression of ENaC in human CF nasal epithelium

Nadine Bangel, Christoph Dahlhoff, Katja Sobczak, Wolf-Michael Weber, Kristina Kusche-Vihrog

Journal:

Journal of Cystic Fibrosis

Year:

2008

Language:

english

File:

PDF, 262 KB

english, 2008

10

The role of ENaC in vascular endothelium

Kusche-Vihrog, Kristina, Jeggle, Pia, Oberleithner, Hans

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2014

Language:

english

File:

PDF, 379 KB

english, 2014

11

Blood pressure and amiloride-sensitive sodium channels in vascular and renal cells

Warnock, David G., Kusche-Vihrog, Kristina, Tarjus, Antoine, Sheng, Shaohu, Oberleithner, Hans, Kleyman, Thomas R., Jaisser, Frederic

Journal:

Nature Reviews Nephrology (formerly Nature Clinical Practice Nephrology)

Year:

2014

Language:

english

File:

PDF, 1.25 MB

english, 2014

12

Simultaneous mechanical stiffness and electrical potential measurements of living vascular endothelial cells using combined atomic force and epifluorescence microscopy

Callies, Chiara, Schön, Peter, Liashkovich, Ivan, Stock, Christian, Kusche-Vihrog, Kristina, Fels, Johannes, Sträter, Alexandra S, Oberleithner, Hans

Journal:

Year:

2009

Language:

english

File:

PDF, 1.00 MB

english, 2009

13

Epithelial Sodium Channel Stiffens the Vascular Endothelium In Vitro and in Liddle Mice

Jeggle, P., Callies, C., Tarjus, A., Fassot, C., Fels, J., Oberleithner, H., Jaisser, F., Kusche-Vihrog, K.

Journal:

Year:

2013

Language:

english

File:

PDF, 706 KB

english, 2013

14

Long-term application of the aldosterone antagonist spironolactone prevents stiff endothelial cell syndrome

Druppel, V., Kusche-Vihrog, K., Grossmann, C., Gekle, M., Kasprzak, B., Brand, E., Pavenstadt, H., Oberleithner, H., Kliche, K.

Journal:

The FASEB Journal

Year:

2013

Language:

english

File:

PDF, 826 KB

english, 2013

15

Feedforward activation of endothelial ENaC by high sodium

Korte, S., Strater, A. S., Druppel, V., Oberleithner, H., Jeggle, P., Grossmann, C., Fobker, M., Nofer, J.-R., Brand, E., Kusche-Vihrog, K.

Journal:

The FASEB Journal

Year:

2014

Language:

english

File:

PDF, 368 KB

english, 2014

16

Potassium softens vascular endothelium and increases nitric oxide release

Oberleithner, H., Callies, C., Kusche-Vihrog, K., Schillers, H., Shahin, V., Riethmuller, C., MacGregor, G. A., de Wardener, H. E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 1.01 MB

english, 2009

17

Salt controls endothelial and vascular phenotype

Kusche-Vihrog, Kristina, Schmitz, Boris, Brand, Eva

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2015

Language:

english

File:

PDF, 1.30 MB

english, 2015

18

Soluble Adenylyl Cyclase in Vascular Endothelium: Gene Expression Control of Epithelial Sodium Channel- , Na+/K+-ATPase- / , and Mineralocorticoid Receptor

Schmitz, B., Nedele, J., Guske, K., Maase, M., Lenders, M., Schelleckes, M., Kusche-Vihrog, K., Brand, S.-M., Brand, E.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.61 MB

english, 2014

19

The epithelial Na+ channel

Kusche-Vihrog, Kristina, Tarjus, Antoine, Fels, Johannes, Jaisser, Frédéric

Journal:

Current Opinion in Nephrology & Hypertension

Year:

2014

Language:

english

File:

PDF, 566 KB

english, 2014

20

C-Reactive Protein Makes Human Endothelium Stiff and Tight

Kusche-Vihrog, K., Urbanova, K., Blanque, A., Wilhelmi, M., Schillers, H., Kliche, K., Pavenstadt, H., Brand, E., Oberleithner, H.

Journal:

Year:

2011

Language:

english

File:

PDF, 472 KB

english, 2011

21

Cystic fibrosis transmembrane conductance regulator is involved in polyphenol-induced swelling of the endothelial glycocalyx

Peters, Wladimir, Kusche-Vihrog, Kristina, Oberleithner, Hans, Schillers, Hermann

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 2.55 MB

english, 2015

22

Membrane potential depolarization decreases the stiffness of vascular endothelial cells

Callies, C., Fels, J., Liashkovich, I., Kliche, K., Jeggle, P., Kusche-Vihrog, K., Oberleithner, H.

Journal:

Journal of Cell Science

Year:

2011

Language:

english

File:

PDF, 648 KB

english, 2011

23

Expression of ENaC and other Transport Proteins in Xenopus Oocytes is Modulated by Intracellular Na+

Kusche-Vihrog, Kristina, Segal, Andrei, Grygorczyk, Ryszard, Bangel-Ruland, Nadine, Van Driessche, Willy, Weber, Wolf-Michael

Journal:

Cellular Physiology and Biochemistry

Year:

2009

Language:

english

File:

PDF, 1.30 MB

english, 2009

24

Endothelial Sodium Channels Trigger Endothelial Salt Sensitivity With Aging

Paar, M., Pavenstadt, H., Kusche-Vihrog, K., Druppel, V., Oberleithner, H., Kliche, K.

Journal:

Year:

2014

Language:

english

File:

PDF, 8.97 MB

english, 2014

25

Aldosterone synthase knockout mouse as a model for sodium-induced endothelial sodium channel up-regulation in vascular endothelium

Jeggle, P., Hofschroer, V., Maase, M., Bertog, M., Kusche-Vihrog, K.

Journal:

The FASEB Journal

Year:

2015

Language:

english

File:

PDF, 1.28 MB

english, 2015

26

Characterization of the Epithelial Sodium Channel δ-Subunit in Human Nasal Epithelium

Bangel-Ruland, Nadine, Sobczak, Katja, Christmann, Tina, Kentrup, Dominik, Langhorst, Hanna, Kusche-Vihrog, Kristina, Weber, Wolf-Michael

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2010

Language:

english

File:

PDF, 538 KB

english, 2010

27

Endothelial cells as vascular salt sensors

Oberleithner, Hans, Kusche-Vihrog, Kristina, Schillers, Hermann

Journal:

Kidney International

Year:

2010

Language:

english

File:

PDF, 485 KB

english, 2010

28

Differential response to endothelial epithelial sodium channel inhibition ex vivo correlates with arterial stiffness in humans

Lenders, Malte, Hofschröer, Verena, Schmitz, Boris, Kasprzak, Bernd, Rohlmann, Astrid, Missler, Markus, Pavenstädt, Hermann, Oberleithner, Hans, Brand, Stefan-Martin, Kusche-Vihrog, Kristina, Brand, E

Journal:

Journal of Hypertension

Year:

2015

Language:

english

File:

PDF, 508 KB

english, 2015

29

Endothelial glycocalyx breakdown is mediated by angiopoietin-2

Lukasz, Alexander, Hillgruber, Carina, Oberleithner, Hans, Kusche-Vihrog, Kristina, Pavenstädt, Hermann, Rovas, Alexandros, Hesse, Bettina, Goerge, Tobias, Kümpers, Philipp

Journal:

Cardiovascular Research

Year:

2017

Language:

english

File:

PDF, 1.54 MB

english, 2017

30

Nanomechanics of the endothelial glycocalyx contribute to Na+-induced vascular inflammation

Schierke, Florian, Wyrwoll, Margot J., Wisdorf, Martin, Niedzielski, Leon, Maase, Martina, Ruck, Tobias, Meuth, Sven G., Kusche-Vihrog, Kristina

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.39 MB

english, 2017

31

Salt-induced Na+/K+-ATPase-α/β expression involves soluble adenylyl cyclase in endothelial cells

Mewes, Mirja, Nedele, Johanna, Schelleckes, Katrin, Bondareva, Olga, Lenders, Malte, Kusche-Vihrog, Kristina, Schnittler, Hans-Joachim, Brand, Stefan-Martin, Schmitz, Boris, Brand, Eva

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2017

Language:

english

File:

PDF, 1.67 MB

english, 2017

32

Blutdruckmessung und Zielblutdruck

Krämer, Bernhard, Hausberg, Martin, Sanner, Bernd, Kusche-Vihrog, Kristina, Weil, Joachim, Weisser, Burkhard, Wenzel, Ulrich, Trenkwalder, Peter

Journal:

DMW - Deutsche Medizinische Wochenschrift

Year:

2017

Language:

german

File:

PDF, 69 KB

german, 2017

33

Endothelial nanomechanics in the context of endothelial (dys)function and inflammation

Fels, Johannes, Kusche-Vihrog, Kristina

Journal:

Antioxidants & Redox Signaling

Year:

2018

Language:

english

File:

PDF, 1.40 MB

english, 2018

34

Sodium renders endothelial cells sticky for red blood cells

Oberleithner, Hans, Wälte, Mike, Kusche-Vihrog, Kristina

Journal:

Frontiers in Physiology

Year:

2015

Language:

english

File:

PDF, 951 KB

english, 2015

35

MP237ENZYMATIC DIGESTION OF THE ENDOTHELIAL GLYCOCALYX IS REGULATED BY THE TIE2 RECEPTOR AND ITS LIGANDS ANGIOPOIETIN-1 AND -2

Lukasz, Alexander, Hillgruber, Carina, Oberleithner, Hans, Hesse, Bettina, Kusche-Vihrog, Kristina, Pavenstädt, Hermann, Görge, Tobias, Kümpers, Philipp

Journal:

Nephrology Dialysis Transplantation

Year:

2017

Language:

english

File:

PDF, 68 KB

english, 2017

36

Combined Raman- and AFM-based detection of biochemical and nanomechanical features of endothelial dysfunction in aorta isolated from ApoE/LDLR−/− mice

Maase, Martina, Rygula, Anna, Pacia, Marta Z., Proniewski, Bartosz, Mateuszuk, Lukasz, Sternak, Magdalena, Kaczor, Agnieszka, Chlopicki, Stefan, Kusche-Vihrog, Kristina

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2018

Language:

english

File:

PDF, 2.89 MB

english, 2018

37

Kongress im Kosmos; Update your knowledge on hypertension;

Kisters, Klaus, Kusche-Vihrog, K.

Journal:

MMW - Fortschritte der Medizin

Year:

2019

Language:

german

File:

PDF, 265 KB

german, 2019

38

Tie2 Activation Promotes Protection and Reconstitution of the Endothelial Glycocalyx in Human Sepsis

Drost, Carolin Christina, Rovas, Alexandros, Kusche-Vihrog, Kristina, Van Slyke, Paul, Kim, Harold, Hoang, Van C, Maynes, Jason T., Wennmann, Dirk Oliver, Pavenstädt, Hermann, Linke, Wolfgang, Lukasz,

Journal:

Thrombosis and Haemostasis

Year:

2019

Language:

english

File:

PDF, 561 KB

english, 2019

39

SP178ANGIOPOIETIN-2 MEDIATES BREAKDOWN OF THE ENDOTHELIAL GLYCOCALYX

Lukasz, Alexander, Hillgruber, Carina, Oberleither, Hans, Kusche-Vihrog, Kristina, Rübig, Eva, Pavenstädt, Hermann, Goerge, Tobias, Kümpers, Philipp

Journal:

Nephrology Dialysis Transplantation

Year:

2016

Language:

english

File:

PDF, 57 KB

english, 2016

40

Symmetric dimethylarginine in dysfunctional high-density lipoprotein mediates endothelial glycocalyx breakdown in chronic kidney disease.

Hesse, Bettina, Rovas, Alexandros, Buscher, Konrad, Kusche-Vihrog, Kristina, Brand, Marcus, Di Marco, Giovana Seno, Kielstein, Jan T., Maas, Renke, Pavenstädt, Hermann, Linke, Wolfgang A., Nofer, Jerz

Journal:

Kidney International

Year:

2019

Language:

english

File:

PDF, 4.17 MB

english, 2019

41

Nanomechanics of the endothelial glycocalyx: from structure to function

Cosgun, ZÃ¼lfÃ¼ Cem, Fels, Benedikt, Kusche-Vihrog, Kristina

Journal:

The American Journal of Pathology

Year:

2020

File:

PDF, 586 KB

2020

42

Erratum: Tie2 Activation Promotes Protection and Reconstitution of the Endothelial Glycocalyx in Human Sepsis

Drost, Carolin Christina, Rovas, Alexandros, Kusche-Vihrog, Kristina, Van Slyke, Paul, Kim, Harold, Hoang, Van C., Maynes, Jason T., Wennmann, Dirk Oliver, PavenstÃ¤dt, Hermann, Linke, Wolfgang, Lukas

Journal:

Thrombosis and Haemostasis

Year:

2019

File:

PDF, 68 KB

2019

43

It takes more than two to tango: mechanosignaling of the endothelial surface

Fels, Benedikt, Kusche-Vihrog, Kristina

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2020

Language:

english

File:

PDF, 941 KB

english, 2020

44

The association between metabolic components and markers of inflammatory and endothelial dysfunction in adolescents, based on the Ewha Birth and Growth Cohort Study

Lee, Hye Ah, Choi, Eun Jeong, Park, Bohyun, Lee, Hwayoung, Hong, Young Sun, Kim, Hae Soon, Shin, Moon-Kyung, Park, Hyesook, Kusche-Vihrog, Kristina

Journal:

Year:

2020

File:

PDF, 615 KB

2020

45

Human CD16+ monocytes promote a pro-atherosclerotic endothelial cell phenotype via CX3CR1-CX3CL1 interaction

Roy-Chowdhury, Eva, Brauns, Nicolas, Helmke, Alexandra, Nordlohne, Johannes, BrÃ¤sen, Jan Hinrich, Schmitz, Jessica, Volkmann, Julia, Fleig, Susanne V, Kusche-Vihrog, Kristina, Haller, Hermann, von Vi

Journal:

Cardiovascular Research

Year:

2020

File:

PDF, 1.26 MB

2020